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Understand Your Immune System & Autoimmunity

Your immune system plays a central role in inflammation, energy, recovery, gut health, allergies and long-term disease risk. Whether you’re dealing with recurring infections, unexplained symptoms, autoimmune concerns, or allergic reactions, our immune system tests help uncover what’s driving your symptoms. From allergy testing and autoimmune blood tests to cytokine panels, viral screening and inflammation markers like the CRP blood test, these assessments give you a clear, science-based understanding of your immune health. For a broader perspective on immune function, read our article on why immune balance matters more than immune boosting.

How i-screen works

01Order online

Choose your preferred blood test and place your order securely through our website.

Browse All Tests

02Receive pathology request form

We'll email you your pathology request form, which you'll need for your blood draw.

03Book an appointment

Book an appointment for your blood draw at a convenient time and location.

04Get your results

Your results land in your secure dashboard with plain-English explanations from our health team, typically within 2–3 weeks.

Choose your focus

Jump straight to the area that best matches your goal or symptoms

Want the most complete picture of your immune and autoimmune health?

Our comprehensive immune panels analyse immune activation, regulation, inflammation, allergy pathways and autoimmune markers. These tests help identify whether your symptoms are driven by overactivity, underactivity or hidden immune dysregulation.

Best seller
6 tests included

Autoimmune diseases affect around 5% of people and are one of the most important health issues in the are UK. There are over 80 different autoimmune diseases ranging from common to very rare.

£199
16 tests included

Cytokines are small proteins that play a crucial role in the immune system and are involved in a wide range of physiological processes, including inflammation, cell growth and differentiation, and tissue repair.

£325
19 tests included

Many nutrients are absolutely essential for good health. It's possible to get most of them from a balanced, real food-based diet, however the typical modern diet lacks several very important nutrients. Find out your nutritional status with this simple nutrition blood test.

£1360

Is your immune system overreactive or underperforming?

Your immune system can become overactive, contributing to autoimmune symptoms, or underactive, increasing susceptibility to infections and chronic inflammation. Autoimmune markers like HLA-B27 and HLA-DQ/DR haplotypes, alongside NK cell, cytokine and broader autoimmune testing, can reveal immune dysregulation and genetic risk factors that may be driving your symptoms.

16 tests included

Cytokines are small proteins that play a crucial role in the immune system and are involved in a wide range of physiological processes, including inflammation, cell growth and differentiation, and tissue repair.

£325
Best seller
6 tests included

Autoimmune diseases affect around 5% of people and are one of the most important health issues in the are UK. There are over 80 different autoimmune diseases ranging from common to very rare.

£199

Do chronic or reactivated viral infections affect your health?

Viruses such as EBV, CMV, Lyme disease and Ross River can stay dormant in the body and reactivate during periods of stress, leading to fatigue, joint pain, immune dysfunction and ongoing inflammation. Viral testing identifies past infection, recent exposure or reactivation so you can better understand whether persistent symptoms are linked to immune-viral interactions.

Best seller
3 tests included

It can be difficult to diagnose EBV because its symptoms so closely resemble a range of other illnesses. However, a blood test can confirm the presence of EBV antibodies in the system, or whether someone has had a recent or past infection.

£136

Could food sensitivities or gut issues be triggering immune symptoms?

Food reactions, allergies and gut-immune interactions can drive inflammation, digestive symptoms, fatigue, eczema, sinus issues and autoimmune flare-ups. Our allergy and food sensitivity panel, including allergy blood tests, food allergy testing and gluten testing, can help identify triggers and uncover underlying immune drivers.

1 test included

Coeliac disease is an autoimmune disorder triggered by gluten that can cause severe digestive problems. It affects 1 in 70 individuals who are mostly diagnosed in adulthood.

£70
120 tests included

A food intolerance occurs when someone has difficulty digesting a particular food - this can lead to symptoms such as intestinal gas, abdominal pain or diarrhoea. Our comprehensive Food Intolerance Check includes screening for 120 foods.

£254
16 tests included

Allergies are on the increase and food allergies, in particular, are becoming more common. Allergies are caused by an overreaction of the body’s immune system to a protein. These proteins may be from foods, pollens, house dust, animal hair or moulds, and are called allergens.

£421
16 tests included

Allergies are on the increase and food allergies, in particular, are becoming more common. Allergies are caused by an overreaction of the body’s immune system to a protein. These proteins may be from foods, pollens, house dust, animal hair or moulds, and are called allergens.

£421
Best seller
91 tests included

Metagenomic shotgun sequencing analysing gut bacteria, digestive function, immunity and inflammation in clinical detail.

£399

Is chronic inflammation a hidden factor?

Chronic low-grade inflammation can drive fatigue, joint pain, cardiovascular risk and accelerated ageing — often without obvious symptoms. CRP, cytokine panels and homocysteine testing can detect this invisible inflammation. Read our deep dive into inflammaging: the slow-burning inflammation that accelerates ageing to understand why managing inflammation is one of the most important steps you can take for long-term health.

16 tests included

Cytokines are small proteins that play a crucial role in the immune system and are involved in a wide range of physiological processes, including inflammation, cell growth and differentiation, and tissue repair.

£325
1 test included

The importance of homocysteine as a marker for health and wellbeing has recently become evident with elevated levels now recognised as a risk factor for cardiovascular disease, osteoporosis and Alzheimer’s.

£110

Frequently Asked Questions

References